LncRNA NameGAS5
Variant TypeSNP
Variant IDrs145204276
Specieshuman
Circulating
Survival
CeRNA
Methylation
Enhancer
Drug
Disease/Traitatherosclerosis
LncRNA Target GenemiR-21
Tissueblood and tissues
Experimentreal-time PCR; cell proliferation assay; luciferase assay; western blot analysis
Function Descriptionthe expression of GAS5 was dramatically upregulated with the presence of GAS5 DEL/DEL, while GAS5 positively regulated PDCD4 expression via inhibiting miR-21 expression.
Pubmed ID30205366
Year2018
TitleAssociation Between the Deletion Allele of Ins/Del Polymorphism (Rs145204276) in the Promoter Region of GAS5 with the Risk of Atherosclerosis
External Links
Links For GAS5GeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For atherosclerosisOMIM Cosmic
Links For rs145204276 dbSNP ClinVar OMIM