LncRNA NamePTCSC2
Variant TypeSNP
Variant IDrs965513
Specieshuman
Circulating
Survival
CeRNA
Methylation
Enhancer
Drug
Disease/Traitpapillary thyroid carcinoma
LncRNA Target GeneFOXE1
Tissueblood, (BCPAP, C64, FTC133 etc.) cell lines
ExperimentqRT-PCR, genotyping
Function DescriptionTranscripts of PTCSC2 are downregulated in PTC tumors. The risk allele [A] of rs965513 was significantly associated with low expression of unspliced PTCSC2 in unaffected thyroid tissue.
Pubmed ID25303483
Year2015
TitleGenetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR and a novel lincRNA gene, PTCSC2
External Links
Links For PTCSC2GeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For papillary thyroid carcinomaOMIM Cosmic
Links For rs965513 dbSNP ClinVar OMIM