Detailed information
| LncRNA Name | RERT-lncRNA |
| Variant Type | SNP |
| Variant ID | rs10680577 |
| Species | human |
| Circulating | ✓ |
| Survival | ✕ |
| CeRNA | ✕ |
| Methylation | ✕ |
| Enhancer | ✕ |
| Drug | ✕ |
| Disease/Trait | hepatocellular carcinoma |
| LncRNA Target Gene | EGLN2 |
| Tissue | blood, hepatocellular carcinoma tissue |
| Experiment | genotyping, luciferase reporter assay, real-time PCR, western blot |
| Function Description | Rs10680577 contributes to hepatocarcinogenesis, possibly by affecting RERT-lncRNA structure and subsequently EGLN2 expression, making it a promising biomarker for early diagnosis of HCC. |
| Pubmed ID | 23026137 |
| Year | 2012 |
| Title | An Insertion/deletion Polymorphism within RERT-lncRNA Modulates Hepatocellular Carcinoma Risk |
| External Links | |
|---|---|
| Links For RERT-lncRNA | GeneCards HGNC NONCODE LncRNAWiki lncrnadb |
| Links For hepatocellular carcinoma | OMIM Cosmic |
| Links For rs10680577 | dbSNP ClinVar OMIM |