LncRNA NameRERT-lncRNA
Variant TypeSNP
Variant IDrs10680577
Specieshuman
Circulating
Survival
CeRNA
Methylation
Enhancer
Drug
Disease/Traithepatocellular carcinoma
LncRNA Target GeneEGLN2
Tissueblood, hepatocellular carcinoma tissue
Experimentgenotyping, luciferase reporter assay, real-time PCR, western blot
Function DescriptionRs10680577 contributes to hepatocarcinogenesis, possibly by affecting RERT-lncRNA structure and subsequently EGLN2 expression, making it a promising biomarker for early diagnosis of HCC.
Pubmed ID23026137
Year2012
TitleAn Insertion/deletion Polymorphism within RERT-lncRNA Modulates Hepatocellular Carcinoma Risk
External Links
Links For RERT-lncRNAGeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For hepatocellular carcinomaOMIM Cosmic
Links For rs10680577 dbSNP ClinVar OMIM