LncRNA NameMIAT
Variant TypeSNP
Variant IDrs1061451
Specieshuman
Circulating
Survival
CeRNA
Methylation
Enhancer
Drug
Disease/Traitnon-small cell lung cancer
LncRNA Target GeneMYO1B, SGK1 and WNT9A
Tissuecell lines( A549,H1975 )
Experimentdual luciferase reporter assay; real-time PCR
Function DescriptionC-containing genotypes of MIAT rs1061451 were protective factor of NSCLC, and MIAT, which may act as ceRNA via miR-133a-5p, modulated MYO1B, SGK1 and WNT9A expression level.
Pubmed ID29795987
Year2018
TitleThe lncRNA myocardial infarction associated transcript-centric competing endogenous RNA network in non-small-cell lung cancer
External Links
Links For MIATGeneCards HGNC NONCODE LncRNAWiki lncrnadb
Links For non-small cell lung cancerOMIM Cosmic
Links For rs1061451 dbSNP ClinVar OMIM