Functional data source

• HPRD :Human Protein Reference Database
  
• MINT : Molecular INTeraction database
  
• BIND :Biomolecular INteraction Network Database
  
• BioGRID :The Biological General Repository for Interaction Datasets
  
• INTACT :Open source database system and analysis tools for protein interaction data.
  
• OPHID :An integrate database of predicted interactions between human proteins, which combines the literature-derived human PPI from BIND, HPRD, INTACT, BioGRID and MINT
  
• Gene Ontology :A major bioinformatics initiative with the aim of standardizing the representation of gene and gene product attributes across species and databases.
  

Experimental validated miRNA target databases

• TarBase:A comprehensive database of experimentally supported animal microRNA targets.
  
• miR2Disease : A manually curated database, aims at providing a comprehensive resource of miRNA deregulation in various human diseases.
  
• miRecords :An integrated resource for microRNA–target interactions.
  

Predicted miRNA target databases

• TargetScan:Predicting biological targets of miRNAs by searching for the presence of conserved 8mer and 7mer sites that match the seed region of each miRNA.
  
• PicTar:PicTar is an algorithm for the identification of microRNA targets. This searchable website provides details (3' UTR alignments with predicted sites, links to various public databases ).
  
• miRanda :Predicted microRNA targets & target downregulation scores. Experimentally observed expression patterns.
  
• PITA :PITA starts by scanning the UTR for potential microRNA targets (using the supplied seed matching tools) and then scores each site.
  
• DIANA-microT :An algorithm based on several parameters calculated individually for each microRNA and it combines conserved and non-conserved microRNA recognition elements into a final prediction score.