Pubmed	LncRNA_symbol	LncRNA_id	LncRNA_transcript	LncRNA_transid	Drug	CID	Material_1	Material_2	Material_3	Material_4	Condition	Experiment	Level	Effect	Year	Reference	Support
25078450	SNAR	ENSG00000278768 	-	-	5-Fluorouracil	3385	-	SNU-C4 vs SNU-C4/5-FU and SNU-C5 vs SNU-C5/5-FU	-	-	colon cancer	in vitro	Low	Sensitive	2014	A long non-coding RNA snaR contributes to 5-fluorouracil resistance in human colon cancer cells.	"Down-regulation of snaR decreased cell death after 5-FU treatment, which indicates that snaR loss decreases in vitro sensitivity to 5-FU."
25169763	TUSC7	ENSG00000243197	-	-	5-Fluorouracil	3385	-	-	-	Patient	esophageal squamous cell carcinoma	in vivo	Low	Sensitive	2014	Association of decreased expression of long non-coding RNA LOC285194 with chemoradiotherapy resistance and poor prognosis in esophageal squamous cell carcinoma.	"In other words, patients with low expression of LOC285194 showed resistance to CRT."
25496320	lnc-LEIGC	-	-	-	5-Fluorouracil	3385	MGC-803	-	-	-	gastric carcinoma	in vitro	Low	Sensitive	2014	LEIGC long non-coding RNA acts as a tumor suppressor in gastric carcinoma by inhibiting the epithelial-to-mesenchymal transition.	"Overexpression of LEIGC suppressed tumor growth and cell proliferation, and enhanced the sensitivity of gastric cancer cells to 5-fluorouracil (5-FU), whereas knockdown of LEIGC showed the opposite effect."
22892392	BCAR4	ENSG00000262117	-	-	Antioestrogens	-	ZR-75-1 and MCF7	-	-	-	breast cancer	in vitro	Low	Resistant	2012	BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib.	BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib.
25650269	GAS5-AS1	ENSG00000270084	-	-	AZD8055	25262965	"LNCaP, 22Rv1, PC-3 and DU145"	-	-	-	prostate cancer	in vitro	Low	Sensitive	2015	Reciprocal regulation of GAS5 lncRNA levels and mTOR inhibitor action in prostate cancer cells.	"GAS5 silencing in LNCaP and 22Rv1 cells decreased the sensitivity to mTOR inhibitors, whereas transfection of GAS5 lncRNA sensitized PC-3 and DU 145 cells to these agents."
25650269	GAS5-AS1	ENSG00000270084	-	-	BEZ235	49803145	"LNCaP, 22Rv1, PC-3 and DU145"	-	-	-	prostate cancer	in vitro	Low	Sensitive	2015	Reciprocal regulation of GAS5 lncRNA levels and mTOR inhibitor action in prostate cancer cells.	"GAS5 silencing in LNCaP and 22Rv1 cells decreased the sensitivity to mTOR inhibitors, whereas transfection of GAS5 lncRNA sensitized PC-3 and DU 145 cells to these agents."
25428589	nc-TGP1	-	-	-	Caffeine	2519	1343Delta	-	-	-	fission yeast	in vitro	Low	Sensitive	2014	Long non-coding RNA-mediated transcriptional interference of a permease gene confers drug tolerance in fission yeast.	Detailed analyses of the affected locus revealed that transcription of the nc-tgp1 lncRNA regulates drug tolerance by repressing the adjacent phosphate-responsive permease gene transporter for glycerophosphodiester 1 (tgp1(+)).
26497652	HOTAIR	ENSG00000228630	-	-	Carboplatin	38904	-	-	-	Patient	ovarian cancer	in vivo	Low	Resistant	2015	HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.	Non-coding RNA HOTAIR or its more stable DNAme surrogate may indicate the presence of a subset of cells which confer resistance to carboplatin
23543869	HOTAIR	ENSG00000228630	-	-	Chemotherapy	-	-	-	-	Patient	sarcoma	in vivo	Low	Resistant	2011	Correlation of MTDH/AEG-1 and HOTAIR Expression with Metastasis and Response to Treatment in Sarcoma Patients.	"Reduced expression of both MTDH/AEG-1 and HOTAIR is correlated with a good response to treatment in terms of necrosis, suggesting that levels of MTDH and HOTAIR are potential biomarkers for treatment efficacy."
25250788	lnc-MRPL33-1	XLOC_001406	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	AFAP1-AS1	ENSG00000272620	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	TTC39C-AS1	ENSG00000264745.1	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	lnc-ZNF205-1	ENSG00000263011.1	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	lnc-LIMS3-2	ENSG00000261760.1	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	lnc-SLCO5A1-1	ENSG00000261658.1	lnc-SLCO5A1-1:1	ENST00000562490.1	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	lnc-GDE1-3	ENSG00000259925.1	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	lnc-KCNA3-3	ENSG00000259834.1	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	lnc-MEX3B-4	ENSG00000259692.1	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	LINC00520	ENSG00000258791	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	lnc-RP11-80A15.1.1-2	ENSG00000258657.1	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	ABCC6P1 	ENSG00000256340	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25956062	PVT1	ENSG00000249859	-	-	Cisplatin	2767	-	BGC823 vs BGC823/CDDP and SGC7901 vs SGC7901/CDDP	-	Patient	gastric cancer	in vitro and in vivo	Low	Resistant	2015	Overexpression of long non-coding RNA PVT1 in gastric cancer cells promotes the development of multidrug resistance.	"Overexpression of LncRNA PVT1 in gastric carcinoma promotes the development of MDR, suggesting an efficacious target for reversing MDR in gastric cancer therapy."
25250788	WDR86-AS1	ENSG00000243836.1	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	Low	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"The results demonstrated that lncRNA ENST00000584612 and ENST00000579363 were downregulated and that NR_038200, ENST00000466677 and ENST00000562112 were upregulated in the PR samples compared with PD samples."
25250788	FOXO3B	ENSG00000240445	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
23741487	LINC00210 	ENSG00000231814	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	-	-	non-small-cell lung cancer	in vitro	Low	Resistant	2013	The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.	"For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP."
25250788	HBBP1	ENSG00000229988	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	LINC01277	ENSG00000229017.1	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	SRGAP3-AS2	ENSG00000228723	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
23741487	CES1P1	ENSG00000228695	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	-	-	non-small-cell lung cancer	in vitro	Low	Sensitive	2013	The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.	"For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP."
24155936	HOTAIR	ENSG00000228630	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	Mice	Patient	lung adenocarcinoma	in vitro and in vivo	Low	Resistant	2013	The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21(WAF1/CIP1) expression.	Knockdown of HOTAIR by RNA interference could resensitize the responses of A549/DDP cells to cisplatin both in vitro and in vivo.
25250788	KRT16P2	ENSG00000227300	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	KRT16P2	ENSG00000227300	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	Low	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"The results demonstrated that lncRNA ENST00000584612 and ENST00000579363 were downregulated and that NR_038200, ENST00000466677 and ENST00000562112 were upregulated in the PR samples compared with PD samples."
23741487	lnc-GTPBP1-2	ENSG00000225450.1	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	-	-	non-small-cell lung cancer	in vitro	Low	Sensitive	2013	The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.	"For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP."
25250788	KRT16P1	ENSG00000214856	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25992654	MEG3	ENSG00000214548	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	Mice	-	lung adenocarcinoma	in vitro and in vivo	Low	Sensitive	2015	The Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma.	MEG3 overexpression in A549/DDP cells increased their chemosensitivity to cisplatin both in vitro and in vivo by inhibiting cell proliferation and inducing apoptosis.
25250788	KRT42P	ENSG00000214514	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
24495014	UCA1	ENSG00000214049	-	-	Cisplatin	2767	-	T24 vs T24/CDDP	-	Patient	bladder cancer	in vitro and in vivo	Low	Resistant	2014	Long non-coding RNA UCA1 increases chemoresistance of bladder cancer cells by regulating Wnt signaling.	"Over-expression of UCA1 significantly increases the cell viability during cisplatin treatment, whereas UCA1 knockdown reduces the cell. viability during cisplatin treatment."
22576688	CUDR	ENSG00000214049	-	-	Cisplatin	2767	UM-UC-2	-	-	-	bladder cancer	in vitro	Low	Resistant	2012	Long non-coding RNA UCA1a(CUDR) promotes proliferation and tumorigenesis of bladder cancer.	Overexpression of UCA1a (CUDR) could antagonize cell apoptosis induced by cisplatin and promote the tumorigenicity of UM-UC-2 cells in vivo.
25250788	LNC-AL353997.1-1	ENSG00000205266.5	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	PSORS1C3	ENSG00000204528	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	KRT17P2	ENSG00000186831	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
23741487	TP53TG1	ENSG00000182165	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	-	-	non-small-cell lung cancer	in vitro	Low	Sensitive	2013	The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.	"For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP."
25250788	NAPSB	ENSG00000131401	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	NAPSB	ENSG00000131401	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	Low	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"The results demonstrated that lncRNA ENST00000584612 and ENST00000579363 were downregulated and that NR_038200, ENST00000466677 and ENST00000562112 were upregulated in the PR samples compared with PD samples."
25250788	lnc-GSTM4	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	lnc-IGL	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	LOC283174	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	LOC728537	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	lnc-M1	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	Low	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"The results demonstrated that lncRNA ENST00000584612 and ENST00000579363 were downregulated and that NR_038200, ENST00000466677 and ENST00000562112 were upregulated in the PR samples compared with PD samples."
23741487	uc003bgl.1	-	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	-	-	non-small-cell lung cancer	in vitro	Low	Resistant	2013	The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.	"For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP."
25250788	AC006050.3	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	AC006050.3	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	AC006050.3	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	AC006050.3	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	Low	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	AC015818.3	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	AC022596.2	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	Low	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"The results demonstrated that lncRNA ENST00000584612 and ENST00000579363 were downregulated and that NR_038200, ENST00000466677 and ENST00000562112 were upregulated in the PR samples compared with PD samples."
25250788	AC022596.6	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25250788	AC022596.6	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Resistant	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
23741487	AC090952.4.1	-	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	-	-	non-small-cell lung cancer	in vitro	Low	Sensitive	2013	The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.	"For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP."
25763542	AK022798	-	-	-	Cisplatin	2767	-	SGC7901 vs SGC7901/CDDP and BGC823 vs BGC823/CDDP	-	-	gastric cancer	in vitro	Low	Resistant	2015	Notch 1 promotes cisplatin-resistant gastric cancer formation by upregulating lncRNA AK022798 expression.	These results suggest that Notch 1 can promote the lncRNA AK022798 expression and result in the formation of SGC7901/DDP and BGC823/DDP cells.
23741487	AK123263	-	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	-	-	non-small-cell lung cancer	in vitro	Low	Sensitive	2013	The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.	"For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP."
25250788	AK125699	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
23741487	AK126698	-	-	-	Cisplatin	2767	-	A549 vs A549/CDDP	-	-	non-small-cell lung cancer	in vitro	Low	Sensitive	2013	The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.	"For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP."
25250788	AK293020	-	-	-	Cisplatin	2767	-	-	-	Patient	lung squamous cell carcinoma	in vivo	High	Sensitive	2014	Long noncoding RNAs expression patterns associated with chemo response to cisplatin based chemotherapy in lung squamous cell carcinoma patients.	"Coding-non-coding gene co-expression network identified many lncRNAs, such as lncRNA AC006050.3-003, that potentially played a key role in chemo response."
25468426	GAS5-AS1	ENSG00000270084	-	-	Cycloheximide	6197	HEK293	-	-	-	human cell	in vitro	Low	Sensitive	2015	Development of cytotoxicity-sensitive human cells using overexpression of long non-coding RNAs.	"In particular, dual lncRNA (GAS5 plus IDI2-AS1, or GAS5 plus SNHG15) overexpression sensitized cells to cell death by more cellular stresses."
25468426	SNHG15	ENSG00000232956	-	-	Cycloheximide	6197	HEK293	-	-	-	human cell	in vitro	Low	Sensitive	2015	Development of cytotoxicity-sensitive human cells using overexpression of long non-coding RNAs.	"In particular, dual lncRNA (GAS5 plus IDI2-AS1, or GAS5 plus SNHG15) overexpression sensitized cells to cell death by more cellular stresses."
25468426	IDI2-AS1	ENSG00000232656	-	-	Cycloheximide	6197	HEK293	-	-	-	human cell	in vitro	Low	Sensitive	2015	Development of cytotoxicity-sensitive human cells using overexpression of long non-coding RNAs.	"In particular, dual lncRNA (GAS5 plus IDI2-AS1, or GAS5 plus SNHG15) overexpression sensitized cells to cell death by more cellular stresses."
23676682	GAS5-AS1	ENSG00000270084	-	-	Docetaxel	148124	22Rv1	-	-	-	prostate cancer	in vitro	Low	Sensitive	2013	Long non-coding RNA GAS5 regulates apoptosis in prostate cancer cell lines.	"Induction of 22Rv1 cell death by UV-C irradiation and chemotherapeutic drugs was augmented in cells transiently transfected with GAS5 constructs, and attenuated following down-regulation of GAS5 expression."
26464619	FENDRR	ENSG00000268388	FENDRR:6	NR_036444	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	FENDRR	ENSG00000268388	FENDRR:6	NR_036444	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	MGC12916	ENSG00000266709	LNC-COX10-3:2	NR_026880	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-ADCY9-1	ENSG00000262185.1	LNC-ADCY9-1:7	ENST00000576810	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-CA5A-4	ENSG00000261327.1	LNC-CA5A-4:9	ENST00000568031.1	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-ZNF706-1	ENSG00000261087.1	LNC-ZNF706-1:1	ENST00000565617	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26408180	FOXC2-AS1 	ENSG00000260944	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	Patient	osteosarcoma	in vitro and in vivo	Low	Resistant	2015	A long non-coding RNA contributes to doxorubicin resistance of osteosarcoma.	"Thus, we concluded that lncRNA ODRUL may act as a pro-doxorubicin-resistant molecule through inducing the expression of the classical multidrug resistance-related ABCB1 gene in osteosarcoma cells."
26464619	FOXC2-AS1	ENSG00000260944	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	FOXC2-AS1	ENSG00000260944	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	LINC00944	ENSG00000256128	LINC00944:6	ENST00000545508	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-ANO9-1	ENSG00000255237.1	LNC-ANO9-1:1	ENST00000525893	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-BCAN-1:1	ENSG00000250495	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	SNHG10	ENSG00000247092	SNHG10:3	ENST00000553559	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	SNHG10	ENSG00000247092	SNHG10:8	ENST00000555866	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	SNHG10	ENSG00000247092	SNHG10:3	ENST00000553559	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-RXRG-1	ENSG00000237463.1	lnc-RXRG-1:6	ENST00000415000.1	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-NBPF16-3	ENSG00000232527	LNC-NBPF16-3:5	ENST00000457390	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-NBPF16-3	ENSG00000232527	LNC-NBPF16-3:5	ENST00000457390	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
16569192	PCGEM1	ENSG00000227418	-	-	Doxorubicin (Adriamycin)	31703	LNCaP	-	-	-	prostate cancer	in vitro	Low	Resistant	2006	"Regulation of apoptosis by a prostate-specific and prostate cancer-associated noncoding gene, PCGEM1."	This study demonstrates that PCGEM1 overexpression in LNCaP cell culture model results in the inhibition of apoptosis induced by doxorubicin (DOX).
26464619	C10orf101	ENSG00000227136	lnc-RPS24-3:27	ENST00000476909	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-RPS24-3	ENSG00000227136	LNC-RPS24-3:27	ENST00000476909	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	MIR503HG	ENSG00000223749	MIR503HG:3	ENST00000440570	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	MIR503HG	ENSG00000223749	MIR503HG:3	ENST00000440570	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	MT1CP	ENSG00000205360	-	ENST00000567054	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	LINC01116	ENSG00000163364	LINC01116:6	NR_040001	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
8674037	H19	ENSG00000130600	-	-	Doxorubicin (Adriamycin)	31703	-	HL-60 vs HL-60/ADR	-	-	leukemia	in vitro	Low	Resistant	1996	H19 gene overexpression in atypical multidrug-resistant cells associated with expression of a 95-kilodalton membrane glycoprotein.	This is the first report of H19 gene overexpression accompanying any form of drug resistance.
8674037	H19	ENSG00000130600	-	-	Doxorubicin (Adriamycin)	31703	-	MCF7 vs MCF-7/AdrVp	-	-	breast cancer	in vitro	Low	Resistant	1996	H19 gene overexpression in atypical multidrug-resistant cells associated with expression of a 95-kilodalton membrane glycoprotein.	This is the first report of H19 gene overexpression accompanying any form of drug resistance.
17297456	H19	ENSG00000130600	-	-	Doxorubicin (Adriamycin)	31703	-	HepG2 vs HepG2/ADR	-	-	hepatocellular carcinoma	in vitro	Low	Resistant	2007	Riboregulator H19 induction of MDR1-associated drug resistance in human hepatocellular carcinoma cells.	the H19 gene is believed to induce P-glycoprotein expression and MDR1-associated drug resistance at least in liver cancer cells through regulation of MDR1 promoter methylation.
24874432	Lnc-VLDLR	-	-	-	Doxorubicin (Adriamycin)	31703	HepG2	-	-	-	hepatocellular cancer	in vitro	Low	Resistant	2014	Involvement of extracellular vesicle long noncoding RNA (linc-VLDLR) in tumor cell responses to chemotherapy.	"These data indicate that EV can modulate cell viability during chemotherapeutic stress, and moreover that linc-VLDLR may promote chemoresistance."
24958102	MRUL	-	-	-	Doxorubicin (Adriamycin)	31703	-	SGC7901 vs SGC7901/ADR	-	-	gastric cancer	in vitro	Low	Resistant	2014	Long noncoding RNA MRUL promotes ABCB1 expression in multidrug-resistant gastric cancer cell sublines.	Our findings indicate that MRUL promotes ABCB1 expression and is a potential target to reverse the MDR phenotype of GC MDR cell sublines.
26464619	lnc-PDGFRB	-	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-PHLDA3	-	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-PRSS21	-	-	NR_073012	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-COL6A1-1	-	LNC-COL6A1-1:1	NONHSAT083002	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	uc010lgv.1	-	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	uc010lgv.1	-	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	uc003txt.3	-	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	lnc-RP11-597K23.2.1-2	-	LNC-RP11-597K23.2.1-2:1	NONHSAT047768	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	LINC01116	-	LINC01116:6	NR_040001	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	uc002sts.4	-	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	High	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	uc003txt.3	-	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Resistant	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
26464619	uc002sts.4	-	-	-	Doxorubicin (Adriamycin)	31703	-	MG63 vs MG63/ADR	-	-	osteosarcoma	in vitro	Low	Sensitive	2015	Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.	"Fifteen randomly selected lncRNAs were dysregulated in MG63/DXR cells relative to MG63 cells by qRT-PCR detection, which were consistent with our microarray data."
24184505	ARA	-	-	-	Doxorubicin (Adriamycin)	31703	-	HepG2 vs HepG2/ADR	-	-	liver cancer	in vitro	Low	Resistant	2014	A novel long non-coding RNA-ARA: adriamycin resistance-associated.	ARA expression is significantly associated with adriamycin sensitivity in a panel of breast and liver cancer cell lines and is markedly up-regulated in parental sensitive MCF-7 and HepG2 cell lines after receiving adriamycin treatment.
24184505	ARA	-	-	-	Doxorubicin (Adriamycin)	31703	-	MCF-7 vs MCF-7/ADR	-	-	breast cancer	in vitro	Low	Resistant	2014	A novel long non-coding RNA-ARA: adriamycin resistance-associated.	ARA expression is significantly associated with adriamycin sensitivity in a panel of breast and liver cancer cell lines and is markedly up-regulated in parental sensitive MCF-7 and HepG2 cell lines after receiving adriamycin treatment.
24168400	ERIC	ENSG00000280303	-	-	Etoposide	36462	U2OS and SAOS-2	-	-	-	osteosarcoma	in vitro	Low	Resistant	2013	The long non-coding RNA ERIC is regulated by E2F and modulates the cellular response to DNA damage.	"Furthermore, ERIC levels were increased following DNA damage by the chemotherapeutic drug Etoposide, and inhibition of ERIC expression enhanced Etoposide -induced apoptosis."
8674037	H19	ENSG00000130600	-	-	Etoposide	36462	-	UMCC-1 vs UMCC-1/VP	-	-	small cell lung cancer	in vitro	Low	Resistant	1996	H19 gene overexpression in atypical multidrug-resistant cells associated with expression of a 95-kilodalton membrane glycoprotein.	This is the first report of H19 gene overexpression accompanying any form of drug resistance.
25650269	GAS5-AS1	ENSG00000270084	-	-	Everolimus	6442177	"LNCaP, 22Rv1, PC-3 and DU145"	-	-	-	prostate cancer	in vitro	Low	Sensitive	2015	Reciprocal regulation of GAS5 lncRNA levels and mTOR inhibitor action in prostate cancer cells.	"GAS5 silencing in LNCaP and 22Rv1 cells decreased the sensitivity to mTOR inhibitors, whereas transfection of GAS5 lncRNA sensitized PC-3 and DU 145 cells to these agents."
24703244	GAS5-AS1	ENSG00000270084	-	-	Everolimus	6442177	Jeko-1 and Z-138	-	-	-	mantle cell lymphoma	in vitro	Low	Sensitive	2014	Role of GAS5 noncoding RNA in mediating the effects of rapamycin and its analogues on mantle cell lymphoma cells.	Stimulation of expression of candidate tumor suppressor GAS5 is responsible for much of the cytotoxic and cytostatic effects of rapalogues in MCL.
26296467	BANCR	ENSG00000278910	-	-	Fentanyl	3345	LOVO and SW480	-	-	-	colorectal cancer	in vitro	Low	Sensitive	2015	Fentanyl inhibits the invasion and migration of colorectal cancer cells via inhibiting the negative regulation of Ets-1 on BANCR.	While Ets-1 overexpression inhibited fentanyl-induced effects that could be reversed by BANCR co-overexpression.
25482516	RNPS1P1	ENSG00000250896	-	ENST00000507437	Gefitinib	123631	-	PC9 vs PC9/GR	-	-	non-small cell lung cancer	in vitro	Low	Resistant	2015	Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer.	"To the best of our knowledge, the results showed for the first time that differentially expressed lncRNAs responded to EGFR-TKIs resistance in NSCLC cells."
25482516	lnc-TMEM30B-3	ENSG00000250548	LNC-TMEM30B-3:4	ENST00000508827	Gefitinib	123631	-	PC9 vs PC9/GR	-	-	non-small cell lung cancer	in vitro	Low	Resistant	2015	Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer.	"To the best of our knowledge, the results showed for the first time that differentially expressed lncRNAs responded to EGFR-TKIs resistance in NSCLC cells."
25482516	RPL23P11	ENSG00000226407	-	ENST00000418077	Gefitinib	123631	-	PC9 vs PC9/GR	-	-	non-small cell lung cancer	in vitro	Low	Sensitive	2015	Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer.	"To the best of our knowledge, the results showed for the first time that differentially expressed lncRNAs responded to EGFR-TKIs resistance in NSCLC cells."
25482516	LOC100129554	ENSG00000205695	-	ENST00000381279	Gefitinib	123631	-	PC9 vs PC9/GR	-	-	non-small cell lung cancer	in vitro	Low	Sensitive	2015	Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer.	"To the best of our knowledge, the results showed for the first time that differentially expressed lncRNAs responded to EGFR-TKIs resistance in NSCLC cells."
25482516	NR_026685	-	-	NR_026685	Gefitinib	123631	-	PC9 vs PC9/GR	-	-	non-small cell lung cancer	in vitro	Low	Resistant	2015	Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer.	"To the best of our knowledge, the results showed for the first time that differentially expressed lncRNAs responded to EGFR-TKIs resistance in NSCLC cells."
25482516	BC087858	-	-	-	Gefitinib	123631	-	PC9 vs PC9/GR	-	-	non-small cell lung cancer	in vitro	Low	Resistant	2015	Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer.	"To the best of our knowledge, the results showed for the first time that differentially expressed lncRNAs responded to EGFR-TKIs resistance in NSCLC cells."
25482516	BG188549	-	-	-	Gefitinib	123631	-	PC9 vs PC9/GR	-	-	non-small cell lung cancer	in vitro	Low	Sensitive	2015	Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer.	"To the best of our knowledge, the results showed for the first time that differentially expressed lncRNAs responded to EGFR-TKIs resistance in NSCLC cells."
25482516	BE244504	-	-	-	Gefitinib	123631	-	PC9 vs PC9/GR	-	-	non-small cell lung cancer	in vitro	Low	Sensitive	2015	Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer.	"To the best of our knowledge, the results showed for the first time that differentially expressed lncRNAs responded to EGFR-TKIs resistance in NSCLC cells."
25755691	Lnc-ZNF532	ENSG00000267593	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Resistant	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	lnc-FAT1-3	ENSG00000250658	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	CTC-338M12.5	ENSG00000250222	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
21316338	PVT1	ENSG00000249859	-	-	Gemcitabine	60750	ASPC-1	-	-	-	pancreatic cancer	in vitro	Low	Resistant	2011	Genome-wide screen identifies PVT1 as a regulator of Gemcitabine sensitivity in human pancreatic cancer cells.	We identified the PVT1 gene as a regulator of Gemcitabine sensitivity and showed that functional inactivation of the PVT1 gene led to enhanced Gemcitabine sensitivity in human pancreatic cancer ASPC-1 cells.
25755691	lnc-DRD5-5	ENSG00000249334	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	lnc-ASB5-1	ENSG00000248980.1	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	UBA6-AS1	ENSG00000248049	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	lnc-LMOD1-1	ENSG00000234678.1	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Resistant	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	DDX6P	ENSG00000230056	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	lnc-MRPL39-3	ENSG00000229962	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Resistant	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	CFLP3	ENSG00000228056	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	OR5H7P	ENSG00000187900	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	RP11-169O17.1	-	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Resistant	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	RP11-264P13.2	-	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	RP11-58D2.1	-	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Resistant	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	RP13-824C8.2	-	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Resistant	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	uc.255	-	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	AC144449.1	-	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Resistant	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	AF086204	-	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Resistant	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25755691	CR619813	-	-	-	Gemcitabine	60750	-	SWl990 vs SWl990/GZ	-	-	pancreatic cancer	in vitro	High	Sensitive	2015	Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling.	Differentially expressed long non-coding RNAs in SW1990/GZ (fold change (log 2) > 5).
25428589	nc-TGP1	-	-	-	Hydroxyurea	3657	1343Delta	-	-	-	fission yeast	in vitro	Low	Sensitive	2014	Long non-coding RNA-mediated transcriptional interference of a permease gene confers drug tolerance in fission yeast.	Detailed analyses of the affected locus revealed that transcription of the nc-tgp1 lncRNA regulates drug tolerance by repressing the adjacent phosphate-responsive permease gene transporter for glycerophosphodiester 1 (tgp1(+)).
22892392	BCAR4	ENSG00000262117	-	-	Lapatinib	208908	ZR-75-1 and MCF7	-	-	-	breast cancer	in vitro	Low	Sensitive	2012	BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib.	BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib.
23676682	GAS5-AS1	ENSG00000270084	-	-	Nutlin-3a	11433190	22Rv1	-	-	-	prostate cancer	in vitro	Low	Sensitive	2013	Long non-coding RNA GAS5 regulates apoptosis in prostate cancer cell lines.	"Induction of 22Rv1 cell death by UV-C irradiation and chemotherapeutic drugs was augmented in cells transiently transfected with GAS5 constructs, and attenuated following down-regulation of GAS5 expression."
24391509	NCYM	ENSG00000233718	-	-	NVP-BEZ235	11977753	-	-	Mice	-	neuroblastoma	in vivo	Low	Resistant	2014	"NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3-Beta resulting in the stabilization of MYCN in human neuroblastomas."	"In contrast, tumors caused in MYCN/NCYM double transgenic mice showed chemo-resistance to the drug."
24473064	PCAT-1	ENSG00000253438 	-	-	Olaparib	23725625	LNCaP and Du145	-	Mice	-	prostate cancer	in vitro and in vivo	Low	Sensitive	2014	"PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer."	"PCAT-1 expression produces a functional deficiency in homologous recombination through its repression of the BRCA2 tumor suppressor, which, in turn, imparts a high sensitivity to small-molecule inhibitors of PARP1."
25258543	PVT1	ENSG00000249859	-	-	Paclitaxel	36314	SGC7901	-	-	Patient	gastric cancer	in vitro and in vivo	Low	Resistant	2014	Expression and clinical significance of the long non-coding RNA PVT1 in human gastric cancer.	PVT1 showed higher expression in human gastric cancer tissues than in adjacent non-cancerous tissues and in SGC7901 paclitaxel-resistant cells compared with SGC7901 cells.
12492109	XIST	ENSG00000229807	-	-	Paclitaxel	36314	OVCA680 and OVCA3	-	-	Patient	ovarian cancer	in vitro and in vivo	Low	Sensitive	2002	Relationship of XIST expression and responses of ovarian cancer to chemotherapy.	Subsequent characterization of XIST expression in a panel of female cancer cell lines showed that the expression level of XIST correlates significantly with Taxol sensitivity.
24141629	XIST	ENSG00000229807	-	-	PCI-24781	11749858	Breast Cancer Cells	-	Mice	-	breast cancer	in vitro and in vivo	Low	Resistant	2013	The histone deacetylase inhibitor abexinostat induces cancer stem cells differentiation in breast cancer with low Xist expression.	"Using gene expression profiling, we identified the long noncoding RNA Xist (X-inactive specific transcript) as a biomarker predicting BCL response to HDACi."
25650269	GAS5-AS1	ENSG00000270084	-	-	Sirolimus	5284616	"LNCaP, 22Rv1, PC-3 and DU145"	-	-	-	prostate cancer	in vitro	Low	Sensitive	2015	Reciprocal regulation of GAS5 lncRNA levels and mTOR inhibitor action in prostate cancer cells.	"GAS5 silencing in LNCaP and 22Rv1 cells decreased the sensitivity to mTOR inhibitors, whereas transfection of GAS5 lncRNA sensitized PC-3 and DU 145 cells to these agents."
24703244	GAS5-AS1	ENSG00000270084	-	-	Sirolimus	5284616	Jeko-1 and Z-138	-	-	-	mantle cell lymphoma	in vitro	Low	Sensitive	2014	Role of GAS5 noncoding RNA in mediating the effects of rapamycin and its analogues on mantle cell lymphoma cells.	Stimulation of expression of candidate tumor suppressor GAS5 is responsible for much of the cytotoxic and cytostatic effects of rapalogues in MCL.
24874432	Lnc-VLDLR	-	-	-	Sorafenib	216239	HepG2	-	-	-	hepatocellular cancer	in vitro	Low	Resistant	2014	Involvement of extracellular vesicle long noncoding RNA (linc-VLDLR) in tumor cell responses to chemotherapy.	"These data indicate that EV can modulate cell viability during chemotherapeutic stress, and moreover that linc-VLDLR may promote chemoresistance."
20859285	BCAR4	ENSG00000262117	-	-	Tamoxifen	2733526	ZR-75-1	-	-	Patient	breast cancer	in vitro and in vivo	Low	Resistant	2010	Relevance of BCAR4 in tamoxifen resistance and tumour aggressiveness of human breast cancer.	BCAR4 may have clinical relevance for tumour aggressiveness and tamoxifen resistance.
25650269	GAS5-AS1	ENSG00000270084	-	-	Temsirolimus	6918289	"LNCaP, 22Rv1, PC-3 and DU145"	-	-	-	prostate cancer	in vitro	Low	Sensitive	2015	Reciprocal regulation of GAS5 lncRNA levels and mTOR inhibitor action in prostate cancer cells.	"GAS5 silencing in LNCaP and 22Rv1 cells decreased the sensitivity to mTOR inhibitors, whereas transfection of GAS5 lncRNA sensitized PC-3 and DU 145 cells to these agents."
24703244	GAS5-AS1	ENSG00000270084	-	-	Temsirolimus	6918289	Jeko-1 and Z-138	-	-	-	mantle cell lymphoma	in vitro	Low	Sensitive	2014	Role of GAS5 noncoding RNA in mediating the effects of rapamycin and its analogues on mantle cell lymphoma cells.	Stimulation of expression of candidate tumor suppressor GAS5 is responsible for much of the cytotoxic and cytostatic effects of rapalogues in MCL.
25428589	nc-TGP1	-	-	-	Thiabendazole	5430	1343Delta	-	-	-	fission yeast	in vitro	Low	Sensitive	2014	Long non-coding RNA-mediated transcriptional interference of a permease gene confers drug tolerance in fission yeast.	Detailed analyses of the affected locus revealed that transcription of the nc-tgp1 lncRNA regulates drug tolerance by repressing the adjacent phosphate-responsive permease gene transporter for glycerophosphodiester 1 (tgp1(+)).
24473064	PCAT-1	ENSG00000253438 	-	-	Veliparib	11960529	LNCaP and Du145	-	Mice	-	prostate cancer	in vitro and in vivo	Low	Sensitive	2014	"PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer."	"PCAT-1 expression produces a functional deficiency in homologous recombination through its repression of the BRCA2 tumor suppressor, which, in turn, imparts a high sensitivity to small-molecule inhibitors of PARP1."
8674037	H19	ENSG00000130600	-	-	Verapamil	2520	-	MCF7 vs MCF-7/AdrVp	-	-	breast cancer	in vitro	Low	Resistant	1996	H19 gene overexpression in atypical multidrug-resistant cells associated with expression of a 95-kilodalton membrane glycoprotein.	This is the first report of H19 gene overexpression accompanying any form of drug resistance.
26164760	lnc-SNAPC2-1:1	NONHSAT060865	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	Lnc-DZIP1-1	NONHSAG013992	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	Lnc-SCYL1-1:3	NONHSAG008675	-	NONHSAT022136	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	Lnc-SCYL1-1:3	NONHSAG008675	-	NONHSAT022142	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	Lnc-FBXW4-1	NONHSAG006731	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	NONHSAG000474	NONHSAG000474	-	NONHSAT001122	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	EIF4A1	ENSG00000277957	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	ENSG00000270123.2	ENSG00000270123.2	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	PLA2G4C-AS1	ENSG00000269420	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	SNORD95	ENSG00000264549	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-CWF19L2-1	ENSG00000261098.1	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	LOC100506844	ENSG00000257698	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	Lnc-SH3TC1	ENSG00000251460.1	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-ZBTB49-1	ENSG00000248516	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	NEAT1	ENSG00000245532	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	DUBR	ENSG00000243701	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	MCCC1-AS1	ENSG00000243368	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-ABCC5-1	ENSG00000238020.1	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	CTAGE7P	ENSG00000233122	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	linc-LONRF3	ENSG00000203650	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-ACSF3	ENSG00000180422.3	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
8674037	H19	ENSG00000130600	-	-	Vincristine	5978	-	HL-60 vs HL-60/VCR	-	-	leukemia	in vitro	Low	Resistant	1996	H19 gene overexpression in atypical multidrug-resistant cells associated with expression of a 95-kilodalton membrane glycoprotein.	This is the first report of H19 gene overexpression accompanying any form of drug resistance.
26164760	lnc-ZNF107	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-HSPA9-1	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-IRF5	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-EFCAB8-1	-	lnc-EFCAB8-1:2	NONHSAT079374	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-LIG1	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-MTHFSD	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
24958102	MRUL	-	-	-	Vincristine	5978	-	SGC7901 vs SGC7901/VCR	-	-	gastric cancer	in vitro	Low	Resistant	2014	Long noncoding RNA MRUL promotes ABCB1 expression in multidrug-resistant gastric cancer cell sublines.	Our findings indicate that MRUL promotes ABCB1 expression and is a potential target to reverse the MDR phenotype of GC MDR cell sublines.
26164760	lnc-BRCA1	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-PGS1	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-POLE2	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-RBM38	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-RELA	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	LOC257358	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-RPLP0	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-ULK3-1	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-ZNF140	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-ZNF714	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-ZWINT	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-C19orf44-6	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-PBX4-1	-	LNC-PBX4-1:4	NONHSAT063072	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-DBN1	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-DNAH1	-	-	-	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Sensitive	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."
26164760	lnc-SIKE1-2	-	-	NONHSAT005373	Vincristine	5978	HCT-8	-	-	-	colon cancer	in vitro	High	Resistant	2015	Expression profile analysis of long non-coding RNA associated with vincristine resistance in colon cancer cells by next-generation sequencing.	"Of these, we observed 23 up-regulated and 20 down-regulated lncRNAs (fold change >10.0). This is the first report of the expression profile of lncRNA of VCR-resistant colon cancer cells."