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Curated LncRNA
LncRNA Info
LncRNA:
HOTAIR
LncRNA Id:
ENSG00000228630
Transcript:
-
Compound Info
Compound:
Cisplatin
Pubchem:
2767
NSC Id
-
Experiment Info
Effect:
Resistant
Condition:
lung adenocarcinoma
Throughput:
Low
In vitro:
A549 vs A549/CDDP
In vivo:
Mice || Patient
Literature Info
PMID:
24155936
Year:
2013
Reference:
The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21(WAF1/CIP1) expression.
Support:
Knockdown of HOTAIR by RNA interference could resensitize the responses of A549/DDP cells to cisplatin both in vitro and in vivo.
