Overview

DrugSETs provides users friendly interface for exploring the relationships between lncRNA-TF-gene and 15 drug categories. The current version of DrugSETs documents 16,307 entries of associations between 282 drugs and 1,570 lncRNA-TF-gene regulatory triplets.

Home

1. The introduction of DrugSETs.
2. A quick search for filtering entries. Users can input lncRNA or drug name of interest.
3. Basic information about anticancer drug-triplets association:
4. The number of triplets identified in 15 drug types.
5. The percentage of each drug type.

Search

DrugSETs provide both quick search and advanced search.
The quick search is convenient for users who focus on one of following issues, lncRNA and drug.
The advanced search enable users to input multiple keywords at the same time.
1. Input lncRNA name, lncRNA ensemble ID or drug name to start the search.
2. Input drug name to start the research.
3. Input lncRNA name or lncRNA ensemble ID to start the research.

Browse

Hierarchical classifications of lncRNAs and drugs are presented in the browse page. The matching records will show by clicking name of interest.
1. Drug names are ranked by their initial letters. By clicking on drug name, records that contain this drug will be returned.
2. LncRNA names are ranked by their initial letters. By clicking on lncRNA name, records that contain this lncRNA will be returned.
3. Basic information about anticancer drug-triplets association:
Drug (drug name)
Triplets (drug sensitivity related lncRNA-TF-gene triplets)
lncRNA (lncRNA ensembl ID)
TF (transcription factor ensembl ID)
Gene (gene ensembl ID)

Prediction

DrugSETs provides a therapeutic drug prediction function in the prediction page. The corresponding therapeutic drugs can be obtained by inputting the expression profile data of patients.


1. Click "Select File" to upload the patient's expression profile data.
2. After uploading the patient's expression profile, click "Upload" to obtain the corresponding therapeutic drugs.
3. Click on "Example Data" to download the example file.