FACER (Functional Atlas of Chromatin Epigenetic Regulators) is a compilation of prioritized functional CRs across multiple cancer types, involving their specific functions, biological categories and their roles in cancers. Functional CRs for each cancer type were prioritized by integrating their various features in multiple omics, including the activity (mutation ratio and extent of differential expression), regulation strength from both TF and miRNAs, central roles in protein-protein interaction network and regulation to epigenetic modifications (DNA hyper- and hypomethylation) of CRs. Moreover, according to the prevalence of CRs across cancers, three types of CRs were proposed, including cancer common, specific and and mixed CRs.

FACER contains 640 functional CRs across 33 cancer types. Users could search the interest CR or interest cancer type or both, the results will exhibited the basic biological information, the related cancer types and the detailed multi-omics functional features in the interest cancer type of the corresponding CR.

FACER offers the search and download for basic information and multi-omics features of 640 functional CRs across 33 cancer types.

For a better display and full functionality of our database, please use Google Chrome or Opera.