The usage tutorial

Two tools including ‘lncSim’, and ‘lncDis’, are provided in our system. The details about the usage of these two tools are described as follows.
1. An example for using ‘lncSim’.
The following figure shows the process of searching similar lncRNAs of ‘A2M-AS1’ or searching similarity between ‘A2M-AS1’ and ‘AC008280.5’.

The input page http://www.bio-bigdata.com/IntNetLncSim/lncsim.jsp.
In the input page, users can input a lncRNA name, such as ‘KLF7-IT1’, to search potential associated diseases of it. Alternatively, users can input a disease name, such as ‘liver cancer’, to search potential associated lncRNAs of it.
The result pages　
After submitting a lncRNA name ‘KLF7-IT1’, the potential associated diseases could be listed in descending order of association score. The first column is the rank of score. The second and the third columns represent the inputted lncRNA and its potential associated diseases, respectively. The last column is the association score between ‘KLF7-IT1’ and the disease in this line. All the results can be downloaded from the page.
   After submitting a disease name ‘KLF7-IT1’, the potential associated lncRNAs could be listed in descending order of association score. The first column is the rank of score. The third and the second columns represent the inputted disease and its potential associated lncRNAs, respectively. The last column is the association score between ‘liver cancer’ and the lncRNA in this line. All the results can be downloaded from the page.
2. An example for using ‘lncDis’.
The following shows the process of searching potential associated diseases of ‘KLF7-IT1’ and potential associated lncRNAs of ‘liver cancer’.

The input page http://www.bio-bigdata.com/IntNetLncSim/lncdis.jsp.
In the input page, users can input a lncRNA name, such as ‘KLF7-IT1’, to search potential associated diseases of it. Alternatively, users can input a disease name, such as ‘liver cancer’, to search potential associated lncRNAs of it.
The result pages　
After submitting a lncRNA name ‘KLF7-IT1’, the potential associated diseases could be listed in descending order of association score. The first column is the rank of score. The second and the third columns represent the inputted lncRNA and its potential associated diseases, respectively. The last column is the association score between ‘KLF7-IT1’ and the disease in this line. All the results can be downloaded from the page.
   After submitting a disease name ‘liver cancer’, the potential associated lncRNAs could be listed in descending order of association score. The first column is the rank of score. The third and the second columns represent the inputted disease and its potential associated lncRNAs, respectively. The last column is the association score between ‘liver cancer’ and the lncRNA in this line. All the results can be downloaded from the page.