Details

Home Details


Basic information of CCL14 :

Official Symbol of Gene CCL14
Species Homo sapiens
Entrez Gene ID 6358
Official Full Name C-C motif chemokine ligand 14
Also known as CC-1; CC-3; CKB1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14; HCC-1(1-74); HCC-1/HCC-3
Gene Type protein coding
dbXrefs Ensembl:ENSG00000276409 MIM:601392; AllianceGenome:HGNC:10612
Map Location 17q12

Sample information of multiple sclerosis:

Detected Sample DNA, blood or frozen brain tissue specimens
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 18602166
Year 2008
Title CCL genes in multiple sclerosis and systemic lupus erythematosus

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result this study reveals strong associations with a marker and a haplotype encompassing the CCL14 gene, which suggests that a lupus relevant variant may lie within or in the proximity of this haplotype
Mechanism/Pathway This follow up study aims to refine the roles of previously suggested candidate genes (CC chemokine ligands or CCLs) in multiple sclerosis (MS), and to test these markers in another autoimmune disorder, systemic lupus erythematosus (SLE)