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MSGD is a comprehensive database containing all available gene knowledge related to multiple sclerosis, including variants, mRNA, protein, knockout, drug targets, and high-throughput data. This database is developed through manual extraction and will be updated manually as new data becomes available. MSGD contains 6,255 differential entries collected from 5,485 published articles, encompassing 3,274 variants, 1175 mRNA data, 418 protein information, 306 gene knockout data, 612 drug target details, and 463 high-throughput information.

For the Home interface, users can quickly access our dataset by the quick search toolbar and click on the diagrams to browse the database by different data type. For the Search interface, we provide query results for (i) details of variants, (ii) regulation of mRNA level, (iii) regulation of protein level, (iv) drug information, (v) knockout information, (vi) high-throughput data. For the Browse interface, users have access to the dataset based on different classifications, including data type and species. By clicking on each gene, users can obtain all the basic information about the gene. For the Analysis interface, users have access to all the analyses of the MSGD database: (i) Data statistic; (ii) Function analysis; (iii) Network analysis; (iv) Distribution of variants. For the Submit interface, users are able to submit their data about multiple sclerosis. For the Download interface, users are able to download all data on multiple sclerosis, including variants, mRNA, drug, etc.

1. The main functions of the database are provided in menu bar form.
2. Use the Quick Search toolbar to access our dataset.
3. Click on the diagrams to browse the database by different data type.
5. Users can quickly visit the other online resource by following the links below. Go for it

Search

For the Search interface, we provide query results for (i) details of variants, (ii) regulation of mRNA level, (iii) regulation of protein level, (iv) drug information, (v) knockout information, (vi) high-throughput data.

Quick Search:
1. Input species, SNP, gene name, entrez gene id. 2. Click on the link below to enter the preset options. 3. Click the button to submit.
Advance Search:
1. Drag the input field to select a certain species. 2. Select the data type. 3. Enter a gene. If it is empty, search all genes under these conditions.

Browse

For the Browse interface, users have access to the dataset based on different classifications, including data type and species. Go for it

By clicking on each gene, users can obtain all the basic information about the gene.

Analysis

For the Analysis interface, users have access to all the analyses of the MSGD database: (i) Data statistic; (ii) Function analysis; (iii) Network analysis; (iv) Distribution of variants. Go for it

1. Data statistic:
Statistics on the number of publications from different years, data type and species in MSGD.

2. Function analysis:
The associated gene function of multiple sclerosis in homo sapiens.

3. Network analysis:
Drug-gene network about multiple sclerosis.

4. Distribution of variants:
Distribution information of variants about multiple sclerosis.

Submit

For the Submit interface, users are able to submit their data about multiple sclerosis. Go for it

Select the data type to submit the corresponding file.

Download

For the Download interface, users are able to download all data on multiple sclerosis, including variants, mRNA, drug, etc. Go for it

Click on the data type to get the corresponding file.