Basic information of ERMN :

Official Symbol of Gene	ERMN
Species	Homo sapiens
Entrez Gene ID	57471
Official Full Name	ermin
Also known as	N/A
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000136541 MIM:610072; AllianceGenome:HGNC:29208
Map Location	2q24.1

Sample information of multiple sclerosis:

Detected Sample	peripheral blood
Sample Detail	N/A
Detected Method	RT-PCR
Disease	MS
Disease subtype	RRMS
Population	N/A
Sample Size	50 RRMS patients and 50 age and gender matched healthy controls

Literature information of multiple sclerosis :

Pubmed ID	31123898
Year	2019
Title	Down-regulation of ERMN expression in relapsing remitting multiple sclerosis

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	The results showed a significant decrease in ERMN expression (p = 0.022); whereas, no significant difference was detected in LTN1 expression between two groups (p = 0.935). The reduction in ERMN expression in leukocytes could be the cause of demyelinating process in RR-MS patients. Current findings might also have practical importance in prognosis and targeted therapies.
Mechanism/Pathway	This paper aims to compare the peripheral transcript levels of Ermin (ERMN) (a gene with putative role in cytoskeletal rearrangements during myelinogenesis) and Listerin E3 Ubiquitin Protein Ligase 1 (LTN1) (a gene with functions in regulating innate immune system) between relapsing-remitting MS (RR-MS) patients and healthy controls.