Basic information of NFATC2 :

Official Symbol of Gene	NFATC2
Species	Homo sapiens
Entrez Gene ID	4773
Official Full Name	nuclear factor of activated T cells 2
Also known as	JCOSL; NFAT1; NFATP
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000101096 MIM:600490; AllianceGenome:HGNC:7776
Map Location	20q13.2

Sample information of multiple sclerosis:

Detected Sample	brain
Sample Detail	neuroblastoma cells SK-N-MC
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	N/A

Literature information of multiple sclerosis :

Pubmed ID	21298033
Year	2011
Title	TNF-a Contributes to Caspase-3 Independent Apoptosis in Neuroblastoma Cells: Role of NFAT

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	These data demonstrate that TNF-a promotes FasL expression through NFAT activation in neuroblastoma cells and this event leads to increased apoptosis through independent caspase-3 activation.
Mechanism/Pathway	Gal4hNFATc2(1–415) construct contains the first 415 amino acids of the human NFATc2 fused to the DNA binding domain (DBD) of the yeast Gal4 transcription factor (amino acids 1–147) in the parental Gal4-DBD plasmid