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Basic information of BDNF :

Official Symbol of Gene BDNF
Species Homo sapiens
Entrez Gene ID 627
Official Full Name brain derived neurotrophic factor
Also known as ANON2; BULN2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000176697 MIM:113505; AllianceGenome:HGNC:1033
Map Location 11p14.1

Sample information of multiple sclerosis:

Detected Sample Human U251 glioma cells
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 27235578
Year 2016
Title Title: Elevation of Ser9 phosphorylation of GSK3 is required for HERV-W env-mediated BDNF signaling in human U251 cells

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result These results indicated that phosphorylation of GSK3β at Ser9 might be involved in HERV-W env-induced BDNF expression, and will hopefully improve our understanding of the role of HERV-W env in neurological and psychiatric diseases
Mechanism/Pathway GSK3β signaling pathway in U251 cells