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Basic information of P2RY12 :

Official Symbol of Gene P2RY12
Species Homo sapiens
Entrez Gene ID 64805
Official Full Name purinergic receptor P2Y12
Also known as HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)
Gene Type protein coding
dbXrefs Ensembl:ENSG00000169313 MIM:600515; AllianceGenome:HGNC:18124
Map Location 3q25.1

Sample information of multiple sclerosis:

Detected Sample Human Embryonic Stem Cell, Oligodendrocyte Progenitor Cell
Sample Detail N/A
Detected Method RT-qPCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 28836401
Year 2017
Title Purinergic Receptor Expression and Potential Association with Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cell Development

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result Elucidation of the expression pattern of purinergic receptors and the effects of different subtypes of these receptors in hESC-OPCs may have a promising role in future cell-based therapy or drug design for demyelinating disease.
Mechanism/Pathway A1 AR activation in hESC-derived OPC (hESC-OPCs) developmental processes such as proliferation and differentiation in vitro