Basic information of IL1B :

Official Symbol of Gene	IL1B
Species	Homo sapiens
Entrez Gene ID	3553
Official Full Name	interleukin 1 beta
Also known as	IL-1; IL1F2; IL1beta; IL1-BETA
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000125538 MIM:147720; AllianceGenome:HGNC:5992
Map Location	2q14.1

Sample information of multiple sclerosis:

Detected Sample	Peripheral blood
Sample Detail	THP-1 cells
Detected Method	Flow cytometric analysis
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	N/A

Literature information of multiple sclerosis :

Pubmed ID	9548401
Year	1997
Title	Glatiramer acetate blocks the activation of THP-1 cells by interferon-g

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	These results suggest that glatiramer acetate might alter macrophage effector function and suggest that further studies in human monocytes and macrophages are warranted
Mechanism/Pathway	glatiramer acetate on the human monocytic cell line, THP-1, activated by lipopolysaccharide and interferon-g as a model for macrophages