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Basic information of CD1A :

Official Symbol of Gene CD1A
Species Homo sapiens
Entrez Gene ID 909
Official Full Name CD1a molecule
Also known as R4; T6; CD1; FCB6; HTA1
Gene Type protein coding
dbXrefs Ensembl:ENSG00000158477 MIM:188370; AllianceGenome:HGNC:1634
Map Location 1q23.1

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype RR-MS、SP-MS
Population N/A
Sample Size 270patients /342 control

Literature information of multiple sclerosis :

Pubmed ID 20954848
Year 2010
Title Association of CD1A +622 T/C, +737 G/C and CD1E +6129 A/G Genes Polymorphisms with Multiple Sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result CD1E and CD1A genes may be involved in networks which determine susceptibility to RR-MS and PP-MS, respectively
Mechanism/Pathway functional polymorphisms in two CD1 genes (+622 T/C and +737 G/C in CD1A along with +6129 A/G in CD1E) might be associated with susceptibility to MS