Basic information of HAR1B :
| Official Symbol of Gene | HAR1B |
| Species | Homo sapiens |
| Entrez Gene ID | 768097 |
| Official Full Name | highly accelerated region 1B |
| Also known as | HAR1R; LINC00065; NCRNA00065 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000231133 MIM:610557; AllianceGenome:HGNC:33118 |
| Map Location | 20q13.33 |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | real-time PCR |
| Disease | MS |
| Disease subtype | RRMSã€PPMS |
| Population | N/A |
| Sample Size | 100 MS patients, including 82 relapsing-remitting (RR), 8 primary progressive (PP), and 10 secondary progressive (SP) MS cases, and 100 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 36583781 |
| Year | 2022 |
| Title | The expression profle of HAR1A and HAR1B in the peripheral blood cells of multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | The low serum level of HAR1A may be a potential molecular biomarker for MS diagnosis; however, no discernible diference was detected in the expression level of HAR1B in the blood samples of MS patients |
| Mechanism/Pathway | HAR1A (highly accelerated region 1A) and HAR1B (highly accelerated region 1B) are lncRNA entities found on the 118-bp HAR1 region lie in human chromosome 20q13.33 |
