Basic information of LRPPRC :
| Official Symbol of Gene | LRPPRC |
| Species | Homo sapiens |
| Entrez Gene ID | 10128 |
| Official Full Name | leucine rich pentatricopeptide repeat containing |
| Also known as | LSFC; GP130; LRP130; MC4DN5; CLONE-23970 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000138095 MIM:607544; AllianceGenome:HGNC:15714 |
| Map Location | 2p21 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL6/J mice |
| Sample Size | 29cases/30controls |
Literature information of multiple sclerosis :
| Pubmed ID | 23998422 |
| Year | 2013 |
| Title | Polymerase I pathway inhibitor ameliorates experimental autoimmune encephalomyelitis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | Our findings demonstrate that POL1 pathway inhibition delayed and suppressed the development of EAE and ameliorated the disease in mice with persistent clinical signs. |
| Mechanism/Pathway | POL1 pathway |
