Basic information of POLR1D :
| Official Symbol of Gene | POLR1D |
| Species | Homo sapiens |
| Entrez Gene ID | 51082 |
| Official Full Name | RNA polymerase I and III subunit D |
| Also known as | AC19; RPA9; TCS2; RPA16; RPAC2; RPC16; POLR1C; RPO1-3 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000186184 MIM:613715; AllianceGenome:HGNC:20422 |
| Map Location | 13q12.2 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL6/J mice |
| Sample Size | 29cases/30controls |
Literature information of multiple sclerosis :
| Pubmed ID | 23998422 |
| Year | 2013 |
| Title | Polymerase I pathway inhibitor ameliorates experimental autoimmune encephalomyelitis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | Our findings demonstrate that POL1 pathway inhibition delayed and suppressed the development of EAE and ameliorated the disease in mice with persistent clinical signs. |
| Mechanism/Pathway | POL1 pathway |
