Basic information of RHOA :

Official Symbol of Gene	RHOA
Species	Homo sapiens
Entrez Gene ID	387
Official Full Name	ras homolog family member A
Also known as	ARHA; ARH12; RHO12; EDFAOB; RHOH12
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000067560 MIM:165390; AllianceGenome:HGNC:667
Map Location	3p21.31

Sample information of multiple sclerosis:

Detected Sample	thymus and spleen
Sample Detail	N/A
Detected Method	PCR
Disease	EAE
Disease subtype	N/A
Population	N/A
Sample Size	RhoAfl/flLckCren = 39, RhoAfl/+LckCre+ n = 14, RhoAfl/flLckCre+ n = 12

Literature information of multiple sclerosis :

Pubmed ID	29904389
Year	2018
Title	RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Treatment risk
Result	RhoA is a central regulator of several archetypical T -cell responses, and furthermore points toward RhoA as a new potential therapeutic target in diseases such as MS, where T -cell activity plays a central role.
Mechanism/Pathway	RhoA is central for T cell