Basic information of TAC1 :
| Official Symbol of Gene | TAC1 |
| Species | Homo sapiens |
| Entrez Gene ID | 6863 |
| Official Full Name | tachykinin precursor 1 |
| Also known as | NK2; NPK; NKNA; TAC2; Hs.2563 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000006128 MIM:162320; AllianceGenome:HGNC:11517 |
| Map Location | 7q21.3 |
Sample information of multiple sclerosis:
| Detected Sample | polygenic model |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | PP,PP |
| Population | N/A |
| Sample Size | 305RR，102PP |
Literature information of multiple sclerosis :
| Pubmed ID | 15729363 |
| Year | 2005 |
| Title | Haplotype analysis of the preprotachykinin-1 (TAC1) gene in multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Two-marker haplotypes composed of allelic combinations of TAC1 promoter–intron 1 SNPs were highly significantly associated with MS and more so with the relapsing-remitting form of this disease. While independent reproduction of these data in other data sets is indicated, our work is suggestive for a role of the TAC1 gene in MS |
| Mechanism/Pathway | AC1 promoter–intron 1 SNPs |
