Basic information of OLIG1 :
| Official Symbol of Gene | OLIG1 |
| Species | Homo sapiens |
| Entrez Gene ID | 116448 |
| Official Full Name | oligodendrocyte transcription factor 1 |
| Also known as | BHLHB6; BHLHE21 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000184221 MIM:606385; AllianceGenome:HGNC:16983 |
| Map Location | 21q22.11 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | C57BL/6 mice |
| Sample Size | n =4 mice group |
Literature information of multiple sclerosis :
| Pubmed ID | 28464811 |
| Year | 2017 |
| Title | Effect of catalpol on remyelination through experimental autoimmune encephalomyelitis acting to promote Olig1 and Olig2 expressions in mice |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | These data demonstrated that Catalpol had a strong neuroprotective effect on EAE mice. Catalpol also plays a role in remyelination by promoting the expressions of Olig1 and Olig2 transcription factors. |
| Mechanism/Pathway | increased the protein expressions of NG2 and MBP in mice brains |
