Basic information of TUG1 :
| Official Symbol of Gene | TUG1 |
| Species | Homo sapiens |
| Entrez Gene ID | 55000 |
| Official Full Name | taurine up-regulated 1 |
| Also known as | TI-227H; LINC00080; NCRNA00080 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000253352 MIM:614971; AllianceGenome:HGNC:26066 |
| Map Location | 22q12.2 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL/6 |
| Sample Size | n =48 mice group |
Literature information of multiple sclerosis :
| Pubmed ID | 31394128 |
| Year | 2019 |
| Title | Down-regulation of taurine-up-regulated gene 1 attenuates inflammation by sponging miR-9-5p via targeting NF-κB1/p50 in multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | own-regulation of TUG1 attenuates MS through inhibition of inflammation by sponging miR-9-5p via targeting NF-κB1/p50, suggesting that TUG1 is a potential therapeutic target for MS treatmen |
| Mechanism/Pathway | sponging miR-9-5p via targeting NF-κB1/p50 |
