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Basic information of FOXP3 :

Official Symbol of Gene FOXP3
Species Homo sapiens
Entrez Gene ID 50943
Official Full Name forkhead box P3
Also known as JM2; AIID; IPEX; PIDX; XPID; DIETER
Gene Type protein coding
dbXrefs Ensembl:ENSG00000049768 MIM:300292; AllianceGenome:HGNC:6106
Map Location Xp11.23

Sample information of multiple sclerosis:

Detected Sample brain
Sample Detail N/A
Detected Method PCR
Disease EAE
Disease subtype N/A
Population C57BL/6
Sample Size n = 7mice group

Literature information of multiple sclerosis :

Pubmed ID 28320131
Year 2017
Title Epigenetic and gene expression alterations of FOXP3 in the T cells of EAE mouse model of multiple sclerosi

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result This study suggests that the epigenetic modification of FOXP3 gene is involved in the pathogenesis of EAE and this could be important in therapy in an appropriate and logical statement.
Mechanism/Pathway FOXP3 promoter