Basic information of IL18 :
| Official Symbol of Gene | IL18 |
| Species | Homo sapiens |
| Entrez Gene ID | 3606 |
| Official Full Name | interleukin 18 |
| Also known as | IGIF; IL-18; IL-1g; IL1F4 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000150782 MIM:600953; AllianceGenome:HGNC:5986 |
| Map Location | 11q23.1 |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 101cases/164controls |
Literature information of multiple sclerosis :
| Pubmed ID | 24402877 |
| Year | 2014 |
| Title | Interleukin 18 gene polymorphism is a risk factor for multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | However, the genotype distribution of the IL18 -607 C/A polymorphism in the MS patient group was not significantly different from that of the control group. These data suggest that IL18 gene polymorphisms at position -137 might be a genetic risk factor for MS in the Turkish population. |
| Mechanism/Pathway | IL18 -607 C/A polymorphism |
