Basic information of PRKCA :
| Official Symbol of Gene | PRKCA |
| Species | Homo sapiens |
| Entrez Gene ID | 5578 |
| Official Full Name | protein kinase C alpha |
| Also known as | AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000154229 MIM:176960; AllianceGenome:HGNC:9393 |
| Map Location | 17q24.2 |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | UK |
| Sample Size | 947 trio families |
Literature information of multiple sclerosis :
| Pubmed ID | 15742114 |
| Year | 2005 |
| Title | No evidence for association of the protein kinase C alpha gene with multiple sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | As many groups investigating complex diseases are now embarking upon large case-control studies with the intent of employing haplotype analysis to increase power, the potential to observe false positive association as a result of the difficulty in reliably estimating the frequency of rare alleles is of concern and needs to be remembered |
| Mechanism/Pathway | using the TRANSMIT program |
