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Basic information of IFN-B :

Official Symbol of Gene IFN-B
Species Homo sapiens
Entrez Gene ID 3456
Official Full Name interferon beta 1
Also known as IFB; IFF; IFNB; IFN-beta
Gene Type protein coding
dbXrefs Ensembl:ENSG00000171855 MIM:147640; AllianceGenome:HGNC:5434
Map Location 9p21.3

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail N/A
Detected Method PCR
Disease EAE
Disease subtype N/A
Population N/A
Sample Size n = 5–6 mice group

Literature information of multiple sclerosis :

Pubmed ID 16800783
Year 2006
Title Gene-Based Delivery of IFN-B Is Efficacious in a Murine Model of Experimental Allergic Encephalomyelitis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result A single injection of the MuIFN-B plasmid was as effective in reducing the severity of the disease as an every other day injection of MuIFN-B protein
Mechanism/Pathway An expression plasmid was constructed using the natural MuIFN-B gene driven by the constitutively active CMV promoter