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Basic information of HLA-DPB1 :

Official Symbol of Gene HLA-DPB1
Species Homo sapiens
Entrez Gene ID 3115
Official Full Name major histocompatibility complex, class II, DP beta 1
Also known as DPB1; HLA-DP; HLA-DPB; HLA-DP1B
Gene Type protein coding
dbXrefs Ensembl:ENSG00000223865 MIM:142858; AllianceGenome:HGNC:4940
Map Location 6p21.32

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size 51cases/150controls

Literature information of multiple sclerosis :

Pubmed ID 1420118
Year 1992
Title FREQUENCY OF HLA-DPB1 ALLELES IN MULTIPLE SCLEROSIS PATIENTS FROM NORTHERN IRELAND

Results of multiple sclerosis :

Expression down-regulation
Risk type Disease risk
Result Although present in the controls, linkage disequilibrium between HLA-DPBl*OlOl and HLA-DR17 was not found in multiple sclerosis patients.
Mechanism/Pathway genetically determined susceptibility