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Basic information of HLA-B :

Official Symbol of Gene HLA-B
Species Homo sapiens
Entrez Gene ID 3106
Official Full Name major histocompatibility complex, class I, B
Also known as AS; HLAB; B-4901
Gene Type protein coding
dbXrefs Ensembl:ENSG00000234745 MIM:142830; AllianceGenome:HGNC:4932
Map Location 6p21.33

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size 109cases

Literature information of multiple sclerosis :

Pubmed ID 3207262
Year 1988
Title Complement Allotyping Explains MHC Associations in Multiple Sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result 109 patients have the supratype HLA B7, C4A3, C4B1, BB, DR2 (7,3,1,S,2)
Mechanism/Pathway Analysis of the HLA data revealed increases in alleles previously reported in Caucasians