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Basic information of C4A :

Official Symbol of Gene C4A
Species Homo sapiens
Entrez Gene ID 720
Official Full Name complement C4A (Rodgers blood group)
Also known as C4; RG; C4S; CO4; C4A2; C4A3; C4A4; C4A6; C4AD; CPAMD2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000244731 MIM:120810; AllianceGenome:HGNC:1323
Map Location 6p21.33

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size 109cases

Literature information of multiple sclerosis :

Pubmed ID 3207262
Year 1988
Title Complement Allotyping Explains MHC Associations in Multiple Sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result 109 patients have the supratype HLA B7, C4A3, C4B1, BB, DR2 (7,3,1,S,2)
Mechanism/Pathway Analysis of the HLA data revealed increases in alleles previously reported in Caucasians