Details

Home Details


Basic information of C4B :

Official Symbol of Gene C4B
Species Homo sapiens
Entrez Gene ID 721
Official Full Name complement C4B (Chido blood group)
Also known as CH; C4F; CO4; C4B1; C4B2; C4B3; C4B5; C4BD; C4B12; C4B_2; CPAMD3
Gene Type protein coding
dbXrefs Ensembl:ENSG00000224389 MIM:120820; AllianceGenome:HGNC:1324
Map Location 6p21.33

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size 109cases

Literature information of multiple sclerosis :

Pubmed ID 3207262
Year 1988
Title Complement Allotyping Explains MHC Associations in Multiple Sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result 109 patients have the supratype HLA B7, C4A3, C4B1, BB, DR2 (7,3,1,S,2)
Mechanism/Pathway Analysis of the HLA data revealed increases in alleles previously reported in Caucasians