Basic information of Insr :

Official Symbol of Gene	Insr
Species	Homo sapiens
Entrez Gene ID	16337
Official Full Name	insulin receptor
Also known as	IR; IR-A; IR-B; CD220; 4932439J01Rik; D630014A15Rik
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000005534 AllianceGenome:MGI:96575
Map Location	8 A1.1; 8 1.82 cM

Sample information of multiple sclerosis:

Detected Sample	spinal cord homogenate
Sample Detail	N/A
Detected Method	PCR
Disease	EAE
Disease subtype	N/A
Population	N/A
Sample Size	n = 5–6 mice group

Literature information of multiple sclerosis :

Pubmed ID	6194246
Year	1983
Title	ANTI I-A ANTIBODY SUPPRESSES ACTIVE ENCEPHALOMYELITIS : Treatment Model for Diseases Linked to IR Genes

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	The mechanisms of action of antibody to IR gene products in autoimmune disease are discussed .
Mechanism/Pathway	suppression works by blocking macrophage presentation ofthe encephalitogenic determinant to Tcells