Basic information of IL1RN :
| Official Symbol of Gene | IL1RN |
| Species | Homo sapiens |
| Entrez Gene ID | 3557 |
| Official Full Name | interleukin 1 receptor antagonist |
| Also known as | DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136689 MIM:147679; AllianceGenome:HGNC:6000 |
| Map Location | 2q14.1 |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 132cases/95controls |
Literature information of multiple sclerosis :
| Pubmed ID | 8765338 |
| Year | 1996 |
| Title | An interleukin 1 -receptor-antagonist gene polymorphism is not associated with multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | These findings speak against a gener- alized importance of the IL-lra gene in MS |
| Mechanism/Pathway | IL-lrd is structurally simi- lar to IL-l and their genes are closely located on the long arm of chromosome 2 (2ql4-q21) |
