Basic information of LRPPRC :
| Official Symbol of Gene | LRPPRC |
| Species | Homo sapiens |
| Entrez Gene ID | 10128 |
| Official Full Name | leucine rich pentatricopeptide repeat containing |
| Also known as | LSFC; GP130; LRP130; MC4DN5; CLONE-23970 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000138095 MIM:607544; AllianceGenome:HGNC:15714 |
| Map Location | 2p21 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood mononuclear cells |
| Detected Method | qRT-PCR |
| Disease | MS |
| Disease subtype | BMSS,RRMS |
| Population | N/A |
| Sample Size | RRMS patients(N = 15), BMS patients (N = 20) |
Literature information of multiple sclerosis :
| Pubmed ID | 23077530 |
| Year | 2012 |
| Title | Suppressed RNA-polymerase 1 pathway is associated with benign multiple sclerosis |
Results of multiple sclerosis :
| Expression | down-regulated |
| Risk type | Disease risk |
| Result | Low level of the POL-1 pathway key genes POLR1D (p = 0.001), RRN3 (p = 0.03) and LRPPRC (p = 0.03) is demonstrated in BMB patients as compared with RRMS patients. |
| Mechanism/Pathway | POL-1 pathway key genes |
