Details

Home Details


Basic information of CPSF7 :

Official Symbol of Gene CPSF7
Species Homo sapiens
Entrez Gene ID 79869
Official Full Name cleavage and polyadenylation specific factor 7
Also known as CFIm59
Gene Type protein coding
dbXrefs Ensembl:ENSG00000149532 AllianceGenome:HGNC:30098
Map Location 11q12.2

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail peripheral blood
Detected Method TaqMan Real‐Time PCR
Disease MS
Disease subtype RRMS
Population N/A
Sample Size 50 healthy volunteers and 50 RRMS patients

Literature information of multiple sclerosis :

Pubmed ID 30815864
Year 2019
Title Integrative analysis of OIP5-AS1/HUR1 to discover new potential biomarkers and therapeutic targets in multiple sclerosis

Results of multiple sclerosis :

Expression up-regulated
Risk type Disease risk
Result The results of this study indicate an increase in the expression of HUR1 (p = 0.0001), CPSF7 (p = 0.02), and reduction of CSTF2 expression (p = 0.04). Also, an increase in the expression of OIP5‐AS1 (p = 0.01) was observed in men less than 30 years old.
Mechanism/Pathway N/A