Basic information of MIR145 :
| Official Symbol of Gene | MIR145 |
| Species | Homo sapiens |
| Entrez Gene ID | 406937 |
| Official Full Name | microRNA 145 |
| Also known as | MIRN145; miR-145; miRNA145 |
| Gene Type | ncRNA |
| dbXrefs | Ensembl:ENSG00000276365 MIM:611795; miRBase:MI0000461; AllianceGenome:HGNC:31532 |
| Map Location | 5q32 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood mononuclear cells |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 75 patients with relapsing-remitting MS patients and 75 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 36329419 |
| Year | 2022 |
| Title | Association between miRNA-145 and miRNA-155 expression in peripheral blood mononuclear cells of patients with multiple sclerosis: a case-control study |
Results of multiple sclerosis :
| Expression | down-regulated |
| Risk type | Phenotypic risk |
| Result | We found that expression of miRNA-145 (P=0.012) and miRNA-155 (P=0.005) were partly reduced in patients with relapse-remitting MS in comparison with healthy controls. |
| Mechanism/Pathway | N/A |
