Basic information of IL10 :
| Official Symbol of Gene | IL10 |
| Species | Homo sapiens |
| Entrez Gene ID | 3586 |
| Official Full Name | interleukin 10 |
| Also known as | CSIF; TGIF; GVHDS; IL-10; IL10A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136634 MIM:124092; AllianceGenome:HGNC:5962 |
| Map Location | 1q32.1 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | TH1/17, TH17, and DN cells |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 29150604 |
| Year | 2017 |
| Title | Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis |
Results of multiple sclerosis :
| Expression | down-regulated |
| Risk type | Disease risk |
| Result | We find that TH1/17 cells have elevated expression of CXCR3 and reduced expression of IFNG, CCL3, CLL4, GZMB, and IL10 compared to healthy controls. |
| Mechanism/Pathway | N/A |
