Basic information of MIR590 :
| Official Symbol of Gene | MIR590 |
| Species | Homo sapiens |
| Entrez Gene ID | 693175 |
| Official Full Name | microRNA 590 |
| Also known as | MIRN590; mir-590; hsa-mir-590 |
| Gene Type | ncRNA |
| dbXrefs | Ensembl:ENSG00000207741 MIM:615070; miRBase:MI0003602; AllianceGenome:HGNC:32846 |
| Map Location | 7q11.23 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | PPMS,RRMS,SPMS |
| Population | N/A |
| Sample Size | healthy controls (n=30), RRMS (n=14), PPMS (n=13) and SPMS (n=12) |
Literature information of multiple sclerosis :
| Pubmed ID | 31484947 |
| Year | 2019 |
| Title | Gene Regulatory Networks in Peripheral Mononuclear Cells Reveals Critical Regulatory Modules and Regulators of Multiple Sclerosis |
Results of multiple sclerosis :
| Expression | down-regulated |
| Risk type | Disease risk |
| Result | Based on the score, RFCs were calculated which showed down-regulation of POU3F2_CDK6_hsa-miR-590-3p in PPMS and up-regulation in RRMS and SPMS. |
| Mechanism/Pathway | N/A |
