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Basic information of IL10 :

Official Symbol of Gene IL10
Species Homo sapiens
Entrez Gene ID 3586
Official Full Name interleukin 10
Also known as CSIF; TGIF; GVHDS; IL-10; IL10A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000136634 MIM:124092; AllianceGenome:HGNC:5962
Map Location 1q32.1

Sample information of multiple sclerosis:

Detected Sample peripheral blood samples
Sample Detail peripheral blood samples
Detected Method PCR
Disease MS
Disease subtype N/A
Population the North Staffordshire Royal Infirmary
Sample Size case = 186 patients with MS;control = 211 unrelated Caucasian individuals

Literature information of multiple sclerosis :

Pubmed ID 10580805
Year 1999
Title Interleukin-10 (IL10) promoter polymorphisms and multiple sclerosis

Results of multiple sclerosis :

Expression none
Risk type Disease risk
Result IL10 polymorphism does not appear to be associated with MS or to influence disease progression
Mechanism/Pathway However, from this study it is apparent that there is no inherent genetic influence of IL10 production on the cause of or on the outcome of MS.