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Basic information of H1 :

Official Symbol of Gene H1
Species Homo sapiens
Entrez Gene ID 109740
Official Full Name histocompatibility 1
Also known as H-1
Gene Type protein coding
dbXrefs AllianceGenome:MGI:95882
Map Location chromosome: 7

Sample information of multiple sclerosis:

Detected Sample brain
Sample Detail N/A
Detected Method RT-PCR
Disease EAE
Disease subtype N/A
Population (C57Bl/6 1 DBA/2) 1 C57Bl/6
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 8812062
Year 1996
Title Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result Additionally, major histocompatibility complex (MHC) class I and class II mRNA levels were increased in the CNS of MBP/IFN-g many immune-mediated demyelinating disorders, includ- transgenic mice, and the increase in MHC class I mRNA expression was detected in both white and gray matter regions.
Mechanism/Pathway N/A