Basic information of LIF :
| Official Symbol of Gene | LIF |
| Species | Homo sapiens |
| Entrez Gene ID | 3976 |
| Official Full Name | leukemia inhibitory factor |
| Also known as | CDF; DIA; HILDA; MLPLI |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000128342 MIM:159540; AllianceGenome:HGNC:6596 |
| Map Location | 22q12.2 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | T cell |
| Detected Method | RT-qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 28966652 |
| Year | 2017 |
| Title | Optical coherence tomography and T cell gene expression analysis in patients with benign multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Our results demonstrated that retinal nerve fiber layer was mildly thinned, and T cells had a distinct gene expression profile that included upregulation of interleukin 10 and leukemia inhibitory factor, downregulation of interleukin 6 and neurotensin high affinity receptor 1 (a novel neurotrophin receptor). |
| Mechanism/Pathway | N/A |
