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Basic information of MT-CO2 :

Official Symbol of Gene MT-CO2
Species Homo sapiens
Entrez Gene ID 4513
Official Full Name mitochondrially encoded cytochrome c oxidase II
Also known as COII; MTCO2; COX2
Gene Type protein coding
dbXrefs MIM:516040; AllianceGenome:HGNC:7421
Map Location N/A

Sample information of multiple sclerosis:

Detected Sample PBMC
Sample Detail N/A
Detected Method RT-PCR
Disease MS
Disease subtype N/A
Population N/A
Sample Size 30 MS patients / 30 healthy subjects

Literature information of multiple sclerosis :

Pubmed ID 23901189
Year 2013
Title Investigation of cytocrom c oxidase gene subunits expression on the Multiple sclerosis

Results of multiple sclerosis :

Expression No significance
Risk type Disease risk
Result The results showed that there are not meaning differences in COX2 gene.
Mechanism/Pathway The final respiratory chain complex (complex IV or cytochrome c oxidase [COX]) is the site at which over 90% of oxygen is consumed.There is a common symptom of MS with mitochondrial diseases such as (AD), (PD) and also the point mutation mtDNA can cause damage to the myelin.