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Basic information of TNFSF14 :

Official Symbol of Gene TNFSF14
Species Homo sapiens
Entrez Gene ID 8740
Official Full Name TNF superfamily member 14
Also known as LTg; CD258; HVEML; LIGHT
Gene Type protein coding
dbXrefs Ensembl:ENSG00000125735 MIM:604520; AllianceGenome:HGNC:11930
Map Location 19p13.3

Sample information of multiple sclerosis:

Detected Sample whole blood
Sample Detail N/A
Detected Method qPCR
Disease MS
Disease subtype N/A
Population Italian
Sample Size 39 patients with MS / 16 HCs

Literature information of multiple sclerosis :

Pubmed ID 34353742
Year 2021
Title Genomic and functional evaluation of TNFSF14 in multiple sclerosis susceptibility

Results of multiple sclerosis :

Expression down-rehulation
Risk type Disease risk
Result Expression levels of both the full-length and DTM TNFSF14 isoforms were lower in patients with MS compared with HCs.
Mechanism/Pathway N/A