Basic information of MIRLET7E :
| Official Symbol of Gene | MIRLET7E |
| Species | Homo sapiens |
| Entrez Gene ID | 406887 |
| Official Full Name | microRNA let-7e |
| Also known as | LET7E; let-7e; MIRNLET7E; hsa-let-7e |
| Gene Type | ncRNA |
| dbXrefs | Ensembl:ENSG00000198972 MIM:611250; miRBase:MI0000066; AllianceGenome:HGNC:31482 |
| Map Location | 19q13.41 |
Sample information of multiple sclerosis:
| Detected Sample | PBMCs |
| Sample Detail | N/A |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 22 patients / 22 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 26780721 |
| Year | 2016 |
| Title | Inverse correlation of expression of microRNA-140-5p with progression of multiple sclerosis and differentiation of encephalitogenic T helper type 1 cells |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | We found that microRNA letâ€7e was significantly upâ€regulated in patients with MS. |
| Mechanism/Pathway | Direct binding of microRNAs to their target mRNAs usually suppresses gene expression and facilitates mRNA degradation. |
