Basic information of IL7 :
| Official Symbol of Gene | IL7 |
| Species | Homo sapiens |
| Entrez Gene ID | 3574 |
| Official Full Name | interleukin 7 |
| Also known as | IL-7 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000104432 MIM:146660; AllianceGenome:HGNC:6023 |
| Map Location | 8q21.13 |
Sample information of multiple sclerosis:
| Detected Sample | serum |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | RRMS, PPMS, SPMS |
| Population | N/A |
| Sample Size | 26 MS patients / 26 HC |
Literature information of multiple sclerosis :
| Pubmed ID | 25218211 |
| Year | 2014 |
| Title | Interleukin-7 expression and its effect on natural killer cells in patients with multiple sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | MS patients had significantly lower levels of IL-7 compared with HC. |
| Mechanism/Pathway | Decreased NK cell numbers and impairment of NK cell function are reported in patients with multiple sclerosis (MS). Interleukin-7 (IL-7) is a member of the common gamma-chain (γc) cytokine superfamily that has well documented roles in lymphocyte development and homeostasis. |
