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Basic information of MMP9 :

Official Symbol of Gene MMP9
Species Homo sapiens
Entrez Gene ID 4318
Official Full Name matrix metallopeptidase 9
Also known as GELB; CLG4B; MMP-9; MANDP2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000100985 MIM:120361; AllianceGenome:HGNC:7176
Map Location 20q13.12

Sample information of multiple sclerosis:

Detected Sample peripheral venous puncture
Sample Detail N/A
Detected Method ELISA
Disease MS
Disease subtype CIS, RMS
Population Caucasian
Sample Size 222 MS patients

Literature information of multiple sclerosis :

Pubmed ID 24009164
Year 2014
Title Early detection of neutralizing antibodies to interferon-beta in multiple sclerosis patients: binding antibodies predict neutralizing antibody development

Results of multiple sclerosis :

Expression No significance
Risk type Treatment risk
Result MMP-9 values did not differ between the NAb-positive and NAb-negative treated patient groups at any time point.
Mechanism/Pathway We investigated several molecules which are involved in the mechanisms of action of IFN-b and can be easily determined in serum.