Basic information of CCL2 :
| Official Symbol of Gene | CCL2 |
| Species | Homo sapiens |
| Entrez Gene ID | 6347 |
| Official Full Name | C-C motif chemokine ligand 2 |
| Also known as | HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000108691 MIM:158105; AllianceGenome:HGNC:10618 |
| Map Location | 17q12 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral venous puncture |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | CIS, RMS |
| Population | Caucasian |
| Sample Size | 222 MS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 24009164 |
| Year | 2014 |
| Title | Early detection of neutralizing antibodies to interferon-beta in multiple sclerosis patients: binding antibodies predict neutralizing antibody development |
Results of multiple sclerosis :
| Expression | No significance |
| Risk type | Treatment risk |
| Result | CCL-2 values did not differ between the NAb-positive and NAb-negative treated patient groups at any time point. |
| Mechanism/Pathway | We investigated several molecules which are involved in the mechanisms of action of IFN-b and can be easily determined in serum: the chemokines CCL-2, which is involved in the recruitment of leukocytes. |
