Basic information of CXCL10 :
| Official Symbol of Gene | CXCL10 |
| Species | Homo sapiens |
| Entrez Gene ID | 3627 |
| Official Full Name | C-X-C motif chemokine ligand 10 |
| Also known as | C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000169245 MIM:147310; AllianceGenome:HGNC:10637 |
| Map Location | 4q21.1 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral venous puncture |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | CIS, RMS |
| Population | Caucasian |
| Sample Size | 222 MS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 24009164 |
| Year | 2014 |
| Title | Early detection of neutralizing antibodies to interferon-beta in multiple sclerosis patients: binding antibodies predict neutralizing antibody development |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Treatment risk |
| Result | Concentrations of CXCL-10 was significantly lower in the BAb-positive than BAb-negative group. |
| Mechanism/Pathway | We investigated several molecules which are involved in the mechanisms of action of IFN-b and can be easily determined in serum: the chemokines CXCL-10 ,which is involved in the recruitment of leukocytes. |
